Out-of-hospital surface cooling with a cooling-blanket to induce mild hypothermia in humans after cardiac arrest: a feasibility trial
نویسندگان
چکیده
Mild hypothermia (32-34°C) is a promising new therapy for patients resuscitated from cardiac arrest. Animal studies suggest that early and fast cooling is crucial. Inducing mild hypothermia immediately after successful restoration of spontaneous circulation (ROSC) out-ofhospital remains a challenge. Therefore, a novel coolingblanket (EMCOOLSpad®), independent of any energy source during use, was developed. The aim of the study was to evaluate feasibility and safety of out-of-hospital surface cooling with EMCOOLSpad® in patients successfully resuscitated from cardiac arrest. Results
منابع مشابه
Mild Resuscitative Hypothermia to Improve Neurological Outcome After Cardiac Arrest A Clinical Feasibility Trial
Background and Purpose—Recent animal studies showed that mild resuscitative hypothermia improves neurological outcome when applied after cardiac arrest. In a 3-year randomized, prospective, multicenter clinical trial, we hypothesized that mild resuscitative cerebral hypothermia (32°C to 34°C core temperature) would improve neurological outcome after cardiac arrest. Methods—We lowered patients’ ...
متن کاملMild resuscitative hypothermia to improve neurological outcome after cardiac arrest. A clinical feasibility trial. Hypothermia After Cardiac Arrest (HACA) Study Group.
BACKGROUND AND PURPOSE Recent animal studies showed that mild resuscitative hypothermia improves neurological outcome when applied after cardiac arrest. In a 3-year randomized, prospective, multicenter clinical trial, we hypothesized that mild resuscitative cerebral hypothermia (32 degrees C to 34 degrees C core temperature) would improve neurological outcome after cardiac arrest. METHODS We ...
متن کاملOut-of-hospital therapeutic hypothermia in cardiac arrest victims
Despite many years of research, outcome after cardiac arrest is dismal. Since 2005, the European Resuscitation Council recommends in its guidelines the use of mild therapeutic hypothermia (32-34 degrees) for 12 to 24 hours in patients successfully resuscitated from cardiac arrest. The benefit of resuscitative mild hypothermia (induced after resuscitation) is well established, while the benefit ...
متن کاملComparative evaluation of the usability of 2 different methods to perform mild hypothermia in patients with out-of-hospital cardiac arrest.
BACKGROUND Several studies have shown that mild hypothermia (32-34°C) markedly mitigates brain damage after cardiac arrest (CA). This study aimed to compare the efficacy of the non-invasive cooling device Hilotherm Clinic (Hilotherm GmbH, Germany) with conventional cooling to induce and maintain mild hypothermia in patients after out-of-hospital CA. METHODS 50 adult patients with an indicatio...
متن کاملMild hypothermia during advanced life support: a preliminary study in out-of-hospital cardiac arrest
INTRODUCTION Induction of mild hypothermia after cardiac arrest may confer neuroprotection. We assessed the feasibility, safety and effectiveness of therapeutic infusion of 2 l of normal saline at 4 degrees C before return of spontaneous circulation during cardiopulmonary resuscitation after out of hospital cardiac arrest. METHODS This was a prospective, observational, multicenter clinical tr...
متن کامل